Ĭompiling the application in native 64-bit mode on Microsoft Windows enables faster floating-point operation of the software. It is available as a package in several Linux distributions, including Debian, Fedora, and Arch Linux.
#AUTODOCK 4.2 FOR MAC OS MAC OS#
Platform supportĪutoDock runs on Linux, Mac OS X, SGI IRIX, and Microsoft Windows. Usage of AutoDock has contributed to the discovery of several drugs, including HIV1 integrase inhibitors. AutoGrid for pre-calculating these grids.AutoDock for docking of the ligand to a set of grids describing the target protein.Olson ĪutoDock is widely used and played a role in the development of the first clinically approved HIV-1 integrase inhibitor by Merck & Co. It is available under the Apache license.īoth AutoDock and Vina are currently maintained by Scripps Research, specifically the Center for Computational Structural Biology (CCSB) led by Dr. As of 2009, this number surpassed 1,200.ĪutoDock Vina is a successor of AutoDock, significantly improved in terms of accuracy and performance. In February 2007, a search of the ISI Citation Index showed more than 1,100 publications had been cited using the primary AutoDock method papers. It is used by the and OpenPandemics - COVID-19 projects run at World Community Grid, to search for antivirals against HIV/AIDS and COVID-19. AutoDock is one of the most cited docking software applications in the research community. AutoDock 4 is available under the GNU General Public License. It is especially effective for protein-ligand docking. com /ccsb-scripps /AutoDock-Vina (AutoDock Vina)ĪutoDock is molecular modeling simulation software. GPL (AutoDock), Apache License (AutoDock Vina)Ĭcsb. Linux, Mac OS X, SGI IRIX, and Microsoft Windows